Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12989.176 | 0.9903 | 0.9757 | 0.7997 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12989.176 | 1.0395 | 1.0993 | 0.7997 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12989.176 | 1.0038 | 1.0094 | 0.7997 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12989.176 | 0.9517 | 0.8799 | 0.7997 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12989.176 | 0.9434 | 0.8595 | 0.7997 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12989.176 | 0.9484 | 0.8718 | 0.7997 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12989.176 | 0.8751 | 0.6925 | 0.7997 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 13558.176 | 0.9951 | 0.9776 | 0.4354 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 13558.176 | 0.9699 | 0.8643 | 0.4354 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 13558.176 | 1.0007 | 1.0030 | 0.4354 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 13558.176 | 1.0330 | 1.1550 | 0.4354 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 13558.176 | 0.9497 | 0.7763 | 0.4354 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 13558.176 | 0.9643 | 0.8399 | 0.4354 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 13558.176 | 0.9349 | 0.7133 | 0.4354 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 13558.176 | 1.0093 | 1.0428 | 0.4354 | |
| MDA-MB-361 | HER2amp | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 13558.176 | 0.9132 | 0.6237 | 0.4354 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00000853 | uM | 12959.176 | 0.9104 | 0.7003 | 0.5779 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0000427 | uM | 12959.176 | 0.9001 | 0.6671 | 0.5779 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.000213 | uM | 12959.176 | 0.9250 | 0.7478 | 0.5779 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00107 | uM | 12959.176 | 0.9207 | 0.7335 | 0.5779 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.00533 | uM | 12959.176 | 0.9333 | 0.7749 | 0.5779 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.0267 | uM | 12959.176 | 0.9412 | 0.8009 | 0.5779 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.133 | uM | 12959.176 | 0.9425 | 0.8052 | 0.5779 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 0.667 | uM | 12959.176 | 0.9288 | 0.7600 | 0.5779 | |
| MDA-MB-415 | HR+ | Luminal | Dichloroacetate | PDK | PDK | 3.33 | uM | 12959.176 | 0.9171 | 0.7219 | 0.5779 |