Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9583.037 | 0.6204 | 0.3484 | 1.2109 | |
| MCF7 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9583.037 | 0.6011 | 0.3136 | 1.2109 | |
| MCF7 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9583.037 | 0.4324 | 0.0008 | 1.2109 | |
| MCF7 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9583.037 | 0.2455 | -0.3728 | 1.2109 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7876.04 | 1.0092 | 1.0170 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7876.04 | 1.0072 | 1.0132 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7876.04 | 1.0441 | 1.0810 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7876.04 | 0.8604 | 0.7413 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7876.04 | 0.2230 | -0.4982 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7876.04 | 0.1580 | -0.6347 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7876.04 | 0.1450 | -0.6625 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7876.04 | 0.1187 | -0.7193 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7876.04 | 0.0945 | -0.7726 | 1.0852 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7877.05 | 1.0016 | 1.0059 | 0.5502 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7877.05 | 1.0444 | 1.1643 | 0.5502 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7877.05 | 1.0160 | 1.0586 | 0.5502 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7877.05 | 0.8503 | 0.4894 | 0.5502 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7877.05 | 0.1867 | -0.9054 | 0.5502 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7877.05 | 0.1769 | -0.9141 | 0.5502 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7877.05 | 0.1502 | -0.9362 | 0.5502 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7877.05 | 0.1059 | -0.9662 | 0.5502 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7877.05 | 0.0478 | -0.9920 | 0.5502 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 10077.037 | 1.1776 | 1.8706 | 0.4524 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 10077.037 | 1.2292 | 2.1561 | 0.4524 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 10077.037 | 1.1196 | 1.5673 | 0.4524 |