Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 10077.037 | 0.8338 | 0.3382 | 0.4524 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 10077.037 | 0.4937 | -0.5798 | 0.4524 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 10077.037 | 0.4154 | -0.7132 | 0.4524 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 10077.037 | 0.3574 | -0.7943 | 0.4524 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 10077.037 | 0.3243 | -0.8341 | 0.4524 | |
| MDA-MB-134-VI | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 10077.037 | 0.0579 | -0.9963 | 0.4524 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7884.05 | 0.9957 | 0.9776 | 0.3869 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7884.05 | 1.0340 | 1.1806 | 0.3869 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7884.05 | 1.0606 | 1.3285 | 0.3869 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7884.05 | 0.7947 | 0.1041 | 0.3869 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7884.05 | 0.3781 | -0.8381 | 0.3869 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7884.05 | 0.3954 | -0.8183 | 0.3869 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7884.05 | 0.3618 | -0.8556 | 0.3869 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7884.05 | 0.2673 | -0.9340 | 0.3869 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7884.05 | 0.3389 | -0.8780 | 0.3869 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7885.037 | 0.9864 | 0.9609 | 0.6907 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7885.037 | 1.0373 | 1.1090 | 0.6907 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7885.037 | 0.9697 | 0.9128 | 0.6907 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7885.037 | 0.8606 | 0.6092 | 0.6907 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7885.037 | 0.3647 | -0.5357 | 0.6907 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7885.037 | 0.3575 | -0.5489 | 0.6907 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7885.037 | 0.3099 | -0.6332 | 0.6907 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7885.037 | 0.2803 | -0.6828 | 0.6907 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7885.037 | 0.1987 | -0.8073 | 0.6907 | |
| MDA-MB-175-VII | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7885.05 | 0.9613 | 0.8826 | 0.6518 |