Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7491.05 | 0.9588 | 0.8604 | 0.5814 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7491.05 | 1.0503 | 1.1760 | 0.5814 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7491.05 | 0.8861 | 0.6245 | 0.5814 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7491.05 | 0.7241 | 0.1478 | 0.5814 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7491.05 | 0.0388 | -0.9925 | 0.5814 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7491.05 | 0.0091 | -0.9994 | 0.5814 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7491.05 | 0.0067 | -0.9996 | 0.5814 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7491.05 | 0.0090 | -0.9994 | 0.5814 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7491.05 | 0.0056 | -0.9997 | 0.5814 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7873.04 | 1.0166 | 1.0152 | 2.1738 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7873.04 | 1.0297 | 1.0271 | 2.1738 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7873.04 | 1.0139 | 1.0127 | 2.1738 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7873.04 | 0.9093 | 0.9144 | 2.1738 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7873.04 | 0.1876 | -0.0738 | 2.1738 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7873.04 | 0.0693 | -0.4142 | 2.1738 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 7873.04 | 0.0671 | -0.4230 | 2.1738 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 20 | uM | 7873.04 | 0.0767 | -0.3862 | 2.1738 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 100 | uM | 7873.04 | 0.0079 | -0.7837 | 2.1738 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 10061.037 | 0.9740 | 0.9701 | 1.7478 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 10061.037 | 1.0793 | 1.0893 | 1.7478 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 10061.037 | 1.0404 | 1.0458 | 1.7478 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 10061.037 | 0.7016 | 0.6329 | 1.7478 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 10061.037 | 0.0784 | -0.5341 | 1.7478 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 10061.037 | 0.0628 | -0.5897 | 1.7478 | |
| MCF12A | NM | Basal B | 17-AAG | HSP90 | HSP90 | 4 | uM | 10061.037 | 0.0557 | -0.6169 | 1.7478 |