Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 10267.131 | 1.0658 | 1.3600 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 10267.131 | 1.1034 | 1.5826 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 10267.131 | 0.9794 | 0.8948 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 10267.131 | 0.9620 | 0.8085 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 10267.131 | 0.9604 | 0.8005 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 10267.131 | 0.6154 | -0.4334 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 10267.131 | 0.1754 | -0.9783 | 0.3849 | |
| UACC-812 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 10267.131 | 0.0666 | -0.9982 | 0.3849 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9045.13 | 1.1020 | 1.1963 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9045.13 | 0.8426 | 0.6957 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9045.13 | 1.0794 | 1.1527 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9045.13 | 0.9686 | 0.9394 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9045.13 | 0.9992 | 0.9985 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9045.13 | 0.9551 | 0.9134 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9045.13 | 0.9871 | 0.9751 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9045.13 | 0.5278 | 0.0804 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 9045.13 | 0.0260 | -0.9407 | 1.0377 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9933.021 | 1.0920 | 1.6092 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9933.021 | 0.8775 | 0.3478 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 9933.021 | 1.1242 | 1.8485 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 9933.021 | 0.8622 | 0.2778 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 9933.021 | 1.0126 | 1.0769 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 9933.021 | 1.0513 | 1.3264 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 9933.021 | 1.1048 | 1.7025 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 9933.021 | 0.9772 | 0.8652 | 0.3311 |