Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7892.017 | 1.0431 | 1.0348 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7892.017 | 1.0041 | 1.0033 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7892.017 | 0.9629 | 0.9694 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7892.017 | 0.4274 | 0.4136 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7892.017 | 0.1069 | -0.1973 | 2.4495 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7893.017 | 1.0771 | 1.0660 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7893.017 | 1.0110 | 1.0096 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7893.017 | 0.9987 | 0.9989 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7893.017 | 1.0002 | 1.0002 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7893.017 | 1.0623 | 1.0535 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7893.017 | 1.0566 | 1.0487 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7893.017 | 0.8941 | 0.9046 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7893.017 | 0.3814 | 0.3129 | 2.2898 | |
| MDA-MB-231 | TNBC | Basal B | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7893.017 | 0.1186 | -0.2117 | 2.2898 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 7896.017 | 1.0417 | 1.0824 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 7896.017 | 1.0157 | 1.0311 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.016 | uM | 7896.017 | 1.0307 | 1.0608 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.08 | uM | 7896.017 | 1.0444 | 1.0877 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.4 | uM | 7896.017 | 1.0500 | 1.0989 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 2 | uM | 7896.017 | 0.9692 | 0.9391 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 10 | uM | 7896.017 | 0.7545 | 0.5138 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 50 | uM | 7896.017 | 0.3183 | -0.3552 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 250 | uM | 7896.017 | 0.1176 | -0.7591 | 1.0113 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.00064 | uM | 9648.017 | 1.0519 | 1.1847 | 0.5727 | |
| MDA-MB-361 | HER2amp | Luminal | Cisplatin | DNA cross-linker | DNA cross-linker | 0.0032 | uM | 9648.017 | 1.0038 | 1.0134 | 0.5727 |