Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7898.018 | 1.1008 | 1.1777 | 1.1279 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 7898.018 | 0.9234 | 0.8636 | 1.1279 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 7898.018 | 1.0499 | 1.0882 | 1.1279 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 7898.018 | 0.9106 | 0.8406 | 1.1279 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 7898.018 | 0.9183 | 0.8544 | 1.1279 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 7898.018 | 0.8222 | 0.6813 | 1.1279 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 7898.018 | 0.8372 | 0.7085 | 1.1279 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 7898.018 | 0.5531 | 0.1830 | 1.1279 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 7898.018 | 0.2167 | -0.4846 | 1.1279 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7899.018 | 1.1023 | 1.0977 | 2.0432 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 7899.018 | 0.8872 | 0.8862 | 2.0432 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 7899.018 | 1.0033 | 1.0032 | 2.0432 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 7899.018 | 0.7816 | 0.7728 | 2.0432 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 7899.018 | 0.8567 | 0.8542 | 2.0432 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 7899.018 | 0.7497 | 0.7370 | 2.0432 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 7899.018 | 0.7589 | 0.7474 | 2.0432 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 7899.018 | 0.6453 | 0.6140 | 2.0432 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 7899.018 | 0.3081 | 0.1240 | 2.0432 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7900.018 | 1.2548 | 1.6287 | 0.8304 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 7900.018 | 0.6656 | 0.2250 | 0.8304 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 7900.018 | 1.0031 | 1.0074 | 0.8304 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 7900.018 | 0.7120 | 0.3284 | 0.8304 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 7900.018 | 1.0137 | 1.0331 | 0.8304 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 7900.018 | 0.7172 | 0.3402 | 0.8304 | ||
| MDA-MB-436 | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 7900.018 | 1.0213 | 1.0514 | 0.8304 |