Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.32 | uM | 10124.034 | 0.6202 | 0.6188 | 2.2594 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 1.6 | uM | 10124.034 | 0.5070 | 0.4807 | 2.2594 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 8 | uM | 10124.034 | 0.4701 | 0.4319 | 2.2594 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 40 | uM | 10124.034 | 0.4339 | 0.3821 | 2.2594 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 200 | uM | 10124.034 | 0.5124 | 0.4876 | 2.2594 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 1000 | uM | 10124.034 | 0.3615 | 0.2749 | 2.2594 | ||
| HMT-3522 S1 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 5000 | uM | 10124.034 | 0.0758 | -0.3617 | 2.2594 | ||
| HMT-3522 T4-2 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10147.034 | 1.0468 | 1.0394 | 2.3470 | ||
| HMT-3522 T4-2 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.064 | uM | 10147.034 | 1.0052 | 1.0044 | 2.3470 | ||
| HMT-3522 T4-2 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 0.32 | uM | 10147.034 | 0.8535 | 0.8695 | 2.3470 | ||
| HMT-3522 T4-2 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 1.6 | uM | 10147.034 | 0.5975 | 0.6059 | 2.3470 | ||
| HMT-3522 T4-2 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 8 | uM | 10147.034 | 0.6222 | 0.6339 | 2.3470 | ||
| HMT-3522 T4-2 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 40 | uM | 10147.034 | 0.6092 | 0.6192 | 2.3470 | ||
| HMT-3522 T4-2 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 200 | uM | 10147.034 | 0.5525 | 0.5532 | 2.3470 | ||
| HMT-3522 T4-2 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 1000 | uM | 10147.034 | 0.0595 | -0.3989 | 2.3470 | ||
| HMT-3522 T4-2 | Unknown | Unknown | CGC-11047 | Polyamine analogue | 5000 | uM | 10147.034 | 0.0099 | -0.7197 | 2.3470 | ||
| Hs 578T | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7861.018 | 2.2654 | 4.2429 | 0.8485 | ||
| Hs 578T | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 7861.018 | 2.1188 | 3.8454 | 0.8485 | ||
| Hs 578T | TNBC | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 7861.018 | 1.3637 | 1.8828 | 0.8485 | ||
| Hs 578T | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 7861.018 | 1.3382 | 1.8193 | 0.8485 | ||
| Hs 578T | TNBC | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 7861.018 | 1.3156 | 1.7631 | 0.8485 | ||
| Hs 578T | TNBC | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 7861.018 | 1.3344 | 1.8098 | 0.8485 | ||
| Hs 578T | TNBC | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 7861.018 | 1.3539 | 1.8582 | 0.8485 | ||
| Hs 578T | TNBC | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 7861.018 | 0.9130 | 0.7967 | 0.8485 | ||
| Hs 578T | TNBC | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 7861.018 | 0.0329 | -0.9642 | 0.8485 |