Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 7865.018 | 0.4451 | 0.0141 | 1.1920 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 7865.018 | 0.0012 | -0.9931 | 1.1920 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9536.006 | 1.1039 | 1.1636 | 1.2564 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9536.006 | 0.9750 | 0.9601 | 1.2564 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9536.006 | 0.6395 | 0.4012 | 1.2564 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9536.006 | 0.9240 | 0.8780 | 1.2564 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9536.006 | 0.9220 | 0.8748 | 1.2564 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9536.006 | 0.9029 | 0.8438 | 1.2564 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9536.006 | 0.8985 | 0.8366 | 1.2564 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9536.006 | 0.8324 | 0.7283 | 1.2564 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9536.006 | 0.0221 | -0.9039 | 1.2564 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10264.026 | 1.0190 | 1.0251 | 1.5047 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 10264.026 | 0.9808 | 0.9744 | 1.5047 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 10264.026 | 0.9192 | 0.8911 | 1.5047 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 10264.026 | 0.7369 | 0.6327 | 1.5047 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 10264.026 | 0.7497 | 0.6515 | 1.5047 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 10264.026 | 0.7715 | 0.6833 | 1.5047 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 10264.026 | 0.7698 | 0.6808 | 1.5047 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 10264.026 | 0.7097 | 0.5925 | 1.5047 | ||
| LY2 | HR+ | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 10264.026 | 0.0532 | -0.7152 | 1.5047 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7868.018 | 1.0987 | 1.0912 | 2.1110 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 7868.018 | 0.9853 | 0.9860 | 2.1110 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 7868.018 | 0.7796 | 0.7775 | 2.1110 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 7868.018 | 0.7664 | 0.7632 | 2.1110 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 7868.018 | 0.7212 | 0.7132 | 2.1110 |