Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 7868.018 | 0.7386 | 0.7325 | 2.1110 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 7868.018 | 0.5910 | 0.5589 | 2.1110 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 7868.018 | 0.1872 | -0.0957 | 2.1110 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 7868.018 | 0.0087 | -0.7886 | 2.1110 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7870.018 | 1.0145 | 1.0128 | 2.2478 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 7870.018 | 0.9373 | 0.9432 | 2.2478 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 7870.018 | 0.7725 | 0.7830 | 2.2478 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 7870.018 | 0.6221 | 0.6193 | 2.2478 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 7870.018 | 0.7006 | 0.7072 | 2.2478 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 7870.018 | 0.7096 | 0.7169 | 2.2478 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 7870.018 | 0.7175 | 0.7254 | 2.2478 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 7870.018 | 0.0777 | -0.3584 | 2.2478 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 7870.018 | 0.0089 | -0.7548 | 2.2478 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 0.0128 | uM | 9551.026 | 0.9915 | 0.9936 | 2.6508 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 0.064 | uM | 9551.026 | 0.8368 | 0.8700 | 2.6508 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 0.32 | uM | 9551.026 | 0.7578 | 0.8013 | 2.6508 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 1.6 | uM | 9551.026 | 0.6353 | 0.6854 | 2.6508 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 8 | uM | 9551.026 | 0.6379 | 0.6880 | 2.6508 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 40 | uM | 9551.026 | 0.6134 | 0.6632 | 2.6508 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 200 | uM | 9551.026 | 0.5904 | 0.6395 | 2.6508 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 1000 | uM | 9551.026 | 0.4065 | 0.4242 | 2.6508 | ||
| MCF 10A | NM | Basal B | CGC-11047 | Polyamine analogue | 5000 | uM | 9551.026 | 0.0108 | -0.6377 | 2.6508 | ||
| MCF 10F | NM | - | CGC-11047 | Polyamine analogue | 0.0128 | uM | 7871.018 | 1.1794 | 1.2956 | 1.1973 | ||
| MCF 10F | NM | - | CGC-11047 | Polyamine analogue | 0.064 | uM | 7871.018 | 0.9794 | 0.9655 | 1.1973 | ||
| MCF 10F | NM | - | CGC-11047 | Polyamine analogue | 0.32 | uM | 7871.018 | 0.9103 | 0.8490 | 1.1973 |