Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 9421.034 | 0.9767 | 0.9256 | 0.6220 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 9421.034 | 0.9070 | 0.7094 | 0.6220 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 9421.034 | 0.8070 | 0.4168 | 0.6220 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 9421.034 | 0.7902 | 0.3696 | 0.6220 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 9421.034 | 0.8356 | 0.4984 | 0.6220 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 9421.034 | 0.7778 | 0.3353 | 0.6220 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 9421.034 | 0.7109 | 0.1556 | 0.6220 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 9421.034 | 0.0571 | -0.9800 | 0.6220 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10263.034 | 0.9524 | 0.7562 | 0.3750 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 0.064 | uM | 10263.034 | 0.9545 | 0.7666 | 0.3750 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 0.32 | uM | 10263.034 | 0.8719 | 0.3876 | 0.3750 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 1.6 | uM | 10263.034 | 0.8418 | 0.2637 | 0.3750 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 8 | uM | 10263.034 | 0.7998 | 0.1026 | 0.3750 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 40 | uM | 10263.034 | 0.8527 | 0.3079 | 0.3750 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 200 | uM | 10263.034 | 0.7991 | 0.0999 | 0.3750 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 1000 | uM | 10263.034 | 0.7589 | -0.0415 | 0.3750 | ||
| HCC2185 | TNBC | Luminal | CGC-11047 | Polyamine analogue | 5000 | uM | 10263.034 | 0.0502 | -0.9993 | 0.3750 | ||
| HCC3153 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.0128 | uM | 10056.034 | 0.9688 | 0.9279 | 0.8648 | ||
| HCC3153 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.064 | uM | 10056.034 | 1.0116 | 1.0269 | 0.8648 | ||
| HCC3153 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 0.32 | uM | 10056.034 | 1.0027 | 1.0062 | 0.8648 | ||
| HCC3153 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1.6 | uM | 10056.034 | 0.7621 | 0.4608 | 0.8648 | ||
| HCC3153 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 8 | uM | 10056.034 | 0.6776 | 0.2751 | 0.8648 | ||
| HCC3153 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 40 | uM | 10056.034 | 0.6183 | 0.1471 | 0.8648 | ||
| HCC3153 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 200 | uM | 10056.034 | 0.5064 | -0.0895 | 0.8648 | ||
| HCC3153 | TNBC | Basal A | CGC-11047 | Polyamine analogue | 1000 | uM | 10056.034 | 0.2340 | -0.6271 | 0.8648 |