Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7807.042 | 1.0390 | 1.0381 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7807.042 | 1.0482 | 1.0470 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7807.042 | 1.0224 | 1.0220 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.137 | uM | 7807.042 | 1.0411 | 1.0402 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.685 | uM | 7807.042 | 1.0100 | 1.0098 | 2.0250 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7808.052 | 0.9898 | 0.9917 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7808.052 | 1.0486 | 1.0386 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7808.052 | 1.0116 | 1.0093 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7808.052 | 1.0431 | 1.0343 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7808.052 | 1.0331 | 1.0264 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7808.052 | 1.0760 | 1.0599 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7808.052 | 0.9907 | 0.9925 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.137 | uM | 7808.052 | 1.0516 | 1.0409 | 2.4842 | |
| HBL-100 | Unknown | Unknown | Cetuximab | EGFR | ErbB | 0.685 | uM | 7808.052 | 0.9931 | 0.9944 | 2.4842 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7809.018 | 0.9887 | 0.9865 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7809.018 | 1.0856 | 1.1005 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0000438 | uM | 7809.018 | 0.9908 | 0.9890 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.000219 | uM | 7809.018 | 1.1059 | 1.1239 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0011 | uM | 7809.018 | 1.1325 | 1.1543 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00548 | uM | 7809.018 | 1.0578 | 1.0682 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.0274 | uM | 7809.018 | 1.0960 | 1.1125 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.137 | uM | 7809.018 | 0.9921 | 0.9906 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.685 | uM | 7809.018 | 0.9716 | 0.9659 | 1.6742 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000175 | uM | 7810.006 | 0.9701 | 0.9385 | 0.9730 | |
| HCC1143 | TNBC | Basal A | Cetuximab | EGFR | ErbB | 0.00000877 | uM | 7810.006 | 1.0284 | 1.0583 | 0.9730 |