Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Celecoxib | COX2 | COX | 66.7 | uM | 10642.136 | 0.9512 | 0.8162 | 0.5193 | |
| MDA-MB-175-VII | HR+ | Luminal | Celecoxib | COX2 | COX | 333 | uM | 10642.136 | 0.9846 | 0.9411 | 0.5193 | |
| MDA-MB-175-VII | HR+ | Luminal | Celecoxib | COX2 | COX | 1670 | uM | 10642.136 | 0.8689 | 0.5259 | 0.5193 | |
| MDA-MB-361 | HER2amp | Luminal | Celecoxib | COX2 | COX | 0.00427 | uM | 10643.136 | 1.0011 | 1.0043 | 0.5141 | |
| MDA-MB-361 | HER2amp | Luminal | Celecoxib | COX2 | COX | 0.0213 | uM | 10643.136 | 1.0339 | 1.1339 | 0.5141 | |
| MDA-MB-361 | HER2amp | Luminal | Celecoxib | COX2 | COX | 0.107 | uM | 10643.136 | 0.9859 | 0.9457 | 0.5141 | |
| MDA-MB-361 | HER2amp | Luminal | Celecoxib | COX2 | COX | 0.533 | uM | 10643.136 | 1.0395 | 1.1565 | 0.5141 | |
| MDA-MB-361 | HER2amp | Luminal | Celecoxib | COX2 | COX | 2.67 | uM | 10643.136 | 1.0659 | 1.2644 | 0.5141 | |
| MDA-MB-361 | HER2amp | Luminal | Celecoxib | COX2 | COX | 13.3 | uM | 10643.136 | 1.0023 | 1.0090 | 0.5141 | |
| MDA-MB-361 | HER2amp | Luminal | Celecoxib | COX2 | COX | 66.7 | uM | 10643.136 | 0.8947 | 0.6108 | 0.5141 | |
| MDA-MB-361 | HER2amp | Luminal | Celecoxib | COX2 | COX | 333 | uM | 10643.136 | 0.9873 | 0.9508 | 0.5141 | |
| MDA-MB-361 | HER2amp | Luminal | Celecoxib | COX2 | COX | 1670 | uM | 10643.136 | 0.7557 | 0.1598 | 0.5141 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 0.00427 | uM | 10644.136 | 0.9900 | 0.9642 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 0.0213 | uM | 10644.136 | 0.9986 | 0.9951 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 0.107 | uM | 10644.136 | 1.0727 | 1.2688 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 0.533 | uM | 10644.136 | 1.0400 | 1.1463 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 2.67 | uM | 10644.136 | 1.0869 | 1.3232 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 13.3 | uM | 10644.136 | 1.0153 | 1.0553 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 66.7 | uM | 10644.136 | 0.3732 | -0.6601 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 333 | uM | 10644.136 | 0.8649 | 0.5406 | 0.5562 | |
| MX1 | Unknown | Unknown | Celecoxib | COX2 | COX | 1670 | uM | 10644.136 | 0.1807 | -0.9077 | 0.5562 | |
| SUM159PT | TNBC | Basal B | Celecoxib | COX2 | COX | 0.00427 | uM | 10520.136 | 1.0719 | 1.0347 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Celecoxib | COX2 | COX | 0.0213 | uM | 10520.136 | 0.8641 | 0.9289 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Celecoxib | COX2 | COX | 0.107 | uM | 10520.136 | 1.0153 | 1.0075 | 4.0331 | |
| SUM159PT | TNBC | Basal B | Celecoxib | COX2 | COX | 0.533 | uM | 10520.136 | 1.0301 | 1.0148 | 4.0331 |