Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7919.011 | 0.0101 | -0.4327 | 3.6508 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7920.075 | 0.9726 | 0.9879 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7920.075 | 0.9781 | 0.9904 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7920.075 | 0.9365 | 0.9715 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7920.075 | 1.0011 | 1.0005 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 7920.075 | 0.9675 | 0.9856 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7920.075 | 0.9208 | 0.9643 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7920.075 | 0.4540 | 0.6832 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7920.075 | 0.0131 | -0.2246 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7920.075 | 0.0088 | -0.2887 | 4.5785 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9844.021 | 1.0696 | 1.0548 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9844.021 | 1.0532 | 1.0421 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9844.021 | 1.0658 | 1.0519 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9844.021 | 1.0757 | 1.0595 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9844.021 | 1.0173 | 1.0139 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9844.021 | 0.9023 | 0.9191 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9844.021 | 0.1436 | -0.0830 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9844.021 | 0.0266 | -0.5344 | 2.4889 | |
| SUM159PT | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9844.021 | 0.0204 | -0.5814 | 2.4889 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7921.011 | 1.0003 | 1.0008 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7921.011 | 0.9988 | 0.9965 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7921.011 | 1.0322 | 1.0959 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7921.011 | 0.9731 | 0.9210 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7921.011 | 1.0418 | 1.1250 | 0.6757 | |
| SUM185PE | TNBC | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7921.011 | 0.9439 | 0.8362 | 0.6757 |