Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7860.011 | 0.0132 | -0.9954 | 0.7135 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9501.011 | 0.9974 | 0.9945 | 0.9301 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9501.011 | 1.0674 | 1.1453 | 0.9301 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9501.011 | 0.9969 | 0.9933 | 0.9301 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9501.011 | 1.0051 | 1.0110 | 0.9301 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9501.011 | 1.0598 | 1.1288 | 0.9301 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9501.011 | 0.9112 | 0.8096 | 0.9301 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9501.011 | 0.0103 | -0.9854 | 0.9301 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9501.011 | 0.0100 | -0.9859 | 0.9301 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9501.011 | 0.0093 | -0.9869 | 0.9301 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7911.011 | 1.0482 | 1.0592 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7911.011 | 1.1503 | 1.1811 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7911.011 | 1.0369 | 1.0454 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7911.011 | 1.0805 | 1.0982 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7911.011 | 1.1004 | 1.1220 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7911.011 | 0.9124 | 0.8896 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7911.011 | 0.4930 | 0.2907 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7911.011 | 0.0222 | -0.8108 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7911.011 | 0.0847 | -0.5663 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10124.021 | 1.1798 | 1.1747 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10124.021 | 0.9527 | 0.9515 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10124.021 | 1.0451 | 1.0451 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10124.021 | 1.0045 | 1.0045 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10124.021 | 0.9651 | 0.9643 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10124.021 | 0.8246 | 0.8139 | 1.9744 |