Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10124.021 | 0.5212 | 0.4377 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10124.021 | 0.0640 | -0.5030 | 1.9744 | |
| HMT-3522 S1 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10124.021 | 0.1483 | -0.2394 | 1.9744 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10147.021 | 1.0771 | 1.0692 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10147.021 | 1.0245 | 1.0223 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10147.021 | 0.9212 | 0.9263 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10147.021 | 1.0354 | 1.0320 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 10147.021 | 0.9918 | 0.9925 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10147.021 | 0.9396 | 0.9438 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10147.021 | 0.7611 | 0.7651 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10147.021 | 0.1213 | -0.2381 | 2.1856 | |
| HMT-3522 T4-2 | Unknown | Unknown | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10147.021 | 0.0107 | -0.7489 | 2.1856 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7862.011 | 0.9928 | 0.9894 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7862.011 | 0.9444 | 0.9181 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7862.011 | 0.9662 | 0.9504 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7862.011 | 0.9910 | 0.9868 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7862.011 | 0.8454 | 0.7692 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7862.011 | 0.8229 | 0.7347 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7862.011 | 0.8426 | 0.7649 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7862.011 | 0.0190 | -0.8893 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7862.011 | 0.0075 | -0.9439 | 1.3695 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7863.011 | 1.0324 | 1.0318 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7863.011 | 1.0110 | 1.0108 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7863.011 | 1.0132 | 1.0130 | 2.0237 | |
| Hs 578T | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7863.011 | 0.9971 | 0.9971 | 2.0237 |