Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10268.12 | 1.1229 | 1.8501 | 0.3272 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10268.12 | 1.5284 | 6.3141 | 0.3272 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10268.12 | 0.8995 | 0.4466 | 0.3272 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 10268.12 | 0.6174 | -0.5421 | 0.3272 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10268.12 | 0.3433 | -0.9239 | 0.3272 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10268.12 | 0.0807 | -0.9991 | 0.3272 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10268.12 | 0.0716 | -0.9994 | 0.3272 | |
| HCC38 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10268.12 | 0.0110 | -1.0000 | 0.3272 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7857.011 | 1.0176 | 1.0336 | 1.0477 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7857.011 | 1.0471 | 1.0897 | 1.0477 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7857.011 | 1.0180 | 1.0343 | 1.0477 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7857.011 | 1.0415 | 1.0792 | 1.0477 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7857.011 | 0.9997 | 0.9994 | 1.0477 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7857.011 | 0.8721 | 0.7551 | 1.0477 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7857.011 | 0.0140 | -0.9660 | 1.0477 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7857.011 | 0.0130 | -0.9684 | 1.0477 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 7857.011 | 0.0099 | -0.9756 | 1.0477 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 7860.011 | 1.0094 | 1.0263 | 0.7135 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 7860.011 | 1.0235 | 1.0662 | 0.7135 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 7860.011 | 0.9824 | 0.9509 | 0.7135 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 7860.011 | 1.0150 | 1.0420 | 0.7135 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 7860.011 | 1.0033 | 1.0094 | 0.7135 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 7860.011 | 0.9795 | 0.9428 | 0.7135 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 7860.011 | 0.0552 | -0.9655 | 0.7135 | |
| HCC70 | TNBC | Basal A | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 7860.011 | 0.0167 | -0.9936 | 0.7135 |