Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7805.05 | 0.9893 | 0.9821 | 1.1940 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7805.05 | 0.6721 | 0.4339 | 1.1940 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7805.05 | 0.6004 | 0.3046 | 1.1940 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 7805.05 | 0.5431 | 0.1995 | 1.1940 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 7805.05 | 0.4344 | -0.0052 | 1.1940 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 7805.05 | 0.3084 | -0.2532 | 1.1940 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 9210.037 | 1.0753 | 1.1859 | 0.8166 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 9210.037 | 0.9726 | 0.9330 | 0.8166 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 9210.037 | 1.0572 | 1.1411 | 0.8166 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 9210.037 | 0.9962 | 0.9908 | 0.8166 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 9210.037 | 0.7125 | 0.3206 | 0.8166 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 9210.037 | 0.5778 | 0.0217 | 0.8166 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 4 | uM | 9210.037 | 0.5277 | -0.0858 | 0.8166 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 20 | uM | 9210.037 | 0.3244 | -0.4962 | 0.8166 | |
| CAMA-1 | HR+ | Luminal | 17-AAG | HSP90 | HSP90 | 100 | uM | 9210.037 | 0.1823 | -0.7513 | 0.8166 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7807.04 | 0.9996 | 0.9996 | 2.1435 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.00128 | uM | 7807.04 | 1.0018 | 1.0017 | 2.1435 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.0064 | uM | 7807.04 | 1.0258 | 1.0239 | 2.1435 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.032 | uM | 7807.04 | 1.0259 | 1.0240 | 2.1435 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.16 | uM | 7807.04 | 0.9983 | 0.9984 | 2.1435 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.8 | uM | 7807.04 | 0.7841 | 0.7854 | 2.1435 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 4 | uM | 7807.04 | 0.2400 | 0.0278 | 2.1435 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 20 | uM | 7807.04 | 0.0924 | -0.3417 | 2.1435 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 100 | uM | 7807.04 | 0.0092 | -0.7759 | 2.1435 | |
| HBL-100 | Unknown | Unknown | 17-AAG | HSP90 | HSP90 | 0.000256 | uM | 7808.05 | 0.8788 | 0.9000 | 2.5177 |