Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7920.016 | 1.1335 | 1.0588 | 4.3230 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7920.016 | 1.0221 | 1.0102 | 4.3230 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7920.016 | 1.0430 | 1.0196 | 4.3230 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7920.016 | 0.7143 | 0.8503 | 4.3230 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 9042.016 | 0.8989 | 0.9267 | 2.8524 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 9042.016 | 1.2489 | 1.1621 | 2.8524 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 9042.016 | 0.9933 | 0.9953 | 2.8524 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 9042.016 | 1.0555 | 1.0382 | 2.8524 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 9042.016 | 1.0681 | 1.0467 | 2.8524 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 9042.016 | 1.0355 | 1.0246 | 2.8524 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 9042.016 | 0.5219 | 0.5923 | 2.8524 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 9042.016 | 0.7438 | 0.8028 | 2.8524 | ||
| SUM159PT | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 9042.016 | 0.8150 | 0.8616 | 2.8524 | ||
| SUM185PE | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7921.016 | 1.0225 | 1.0684 | 0.6622 | ||
| SUM185PE | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7921.016 | 0.9982 | 0.9947 | 0.6622 | ||
| SUM185PE | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7921.016 | 1.0385 | 1.1175 | 0.6622 | ||
| SUM185PE | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7921.016 | 0.9839 | 0.9517 | 0.6622 | ||
| SUM185PE | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7921.016 | 1.0391 | 1.1193 | 0.6622 | ||
| SUM185PE | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7921.016 | 1.0091 | 1.0274 | 0.6622 | ||
| SUM185PE | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7921.016 | 0.9093 | 0.7324 | 0.6622 | ||
| SUM185PE | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7921.016 | 0.0182 | -0.9953 | 0.6622 | ||
| SUM185PE | TNBC | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7921.016 | 0.0073 | -0.9988 | 0.6622 | ||
| SUM229PE | TNBC | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7536.016 | 1.0774 | 1.2464 | 0.6413 | ||
| SUM229PE | TNBC | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7536.016 | 0.8858 | 0.6553 | 0.6413 | ||
| SUM229PE | TNBC | - | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7536.016 | 0.9706 | 0.9089 | 0.6413 |