Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7884.016 | 1.0054 | 1.0238 | 0.4603 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7884.016 | 1.0111 | 1.0485 | 0.4603 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7885.016 | 0.9726 | 0.9236 | 0.7137 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7885.016 | 0.9532 | 0.8701 | 0.7137 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7885.016 | 1.0315 | 1.0889 | 0.7137 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7885.016 | 0.8987 | 0.7221 | 0.7137 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7885.016 | 0.9967 | 0.9908 | 0.7137 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7885.016 | 0.9127 | 0.7598 | 0.7137 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7885.016 | 0.9383 | 0.8294 | 0.7137 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7885.016 | 0.9412 | 0.8372 | 0.7137 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7885.016 | 0.9102 | 0.7529 | 0.7137 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7886.016 | 1.0136 | 1.0379 | 0.7194 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7886.016 | 0.9966 | 0.9905 | 0.7194 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7886.016 | 0.9983 | 0.9951 | 0.7194 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7886.016 | 0.9383 | 0.8304 | 0.7194 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7886.016 | 1.0244 | 1.0681 | 0.7194 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 1.33 | uM | 7886.016 | 0.9319 | 0.8133 | 0.7194 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 6.67 | uM | 7886.016 | 0.9568 | 0.8808 | 0.7194 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 33.3 | uM | 7886.016 | 0.5489 | -0.1312 | 0.7194 | ||
| MDA-MB-175-VII | HR+ | Luminal | (Z)-4-Hydroxytamoxifen | ESR1 | 167 | uM | 7886.016 | 0.8196 | 0.5168 | 0.7194 | ||
| MDA-MB-231 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.000427 | uM | 7892.016 | 0.9995 | 0.9996 | 2.3475 | ||
| MDA-MB-231 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.00213 | uM | 7892.016 | 1.0291 | 1.0246 | 2.3475 | ||
| MDA-MB-231 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0107 | uM | 7892.016 | 0.9592 | 0.9648 | 2.3475 | ||
| MDA-MB-231 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.0533 | uM | 7892.016 | 1.0603 | 1.0505 | 2.3475 | ||
| MDA-MB-231 | TNBC | Basal B | (Z)-4-Hydroxytamoxifen | ESR1 | 0.267 | uM | 7892.016 | 0.9808 | 0.9835 | 2.3475 |