Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15317.203 | 0.8228 | 0.8569 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15317.203 | 0.4860 | 0.5196 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15317.203 | 0.4860 | 0.5196 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15317.203 | 0.2731 | 0.2203 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15317.203 | 0.2731 | 0.2203 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15317.203 | 0.0404 | -0.4104 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 15317.203 | 0.0404 | -0.4104 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15317.203 | 0.0141 | -0.6051 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 15317.203 | 0.0141 | -0.6051 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15317.203 | 0.0147 | -0.5993 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 15317.203 | 0.0147 | -0.5993 | 2.6269 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7487.074 | 0.9700 | 0.9576 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7487.074 | 0.9700 | 0.9576 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7487.074 | 0.9941 | 0.9917 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7487.074 | 0.9941 | 0.9917 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7487.074 | 0.9022 | 0.8601 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7487.074 | 0.9022 | 0.8601 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7487.074 | 0.8208 | 0.7402 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7487.074 | 0.8208 | 0.7402 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7487.074 | 0.5439 | 0.3024 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7487.074 | 0.5439 | 0.3024 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7487.074 | 0.2878 | -0.1683 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7487.074 | 0.2878 | -0.1683 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7487.074 | 0.0777 | -0.6694 | 1.4197 | |
| MCF 10F | NM | - | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7487.074 | 0.0777 | -0.6694 | 1.4197 |