Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14747.203 | 0.9355 | 0.9471 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14747.203 | 0.9355 | 0.9471 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14747.203 | 0.8485 | 0.8721 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14747.203 | 0.8485 | 0.8721 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14747.203 | 0.8657 | 0.8873 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14747.203 | 0.8657 | 0.8873 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14747.203 | 0.3836 | 0.3603 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14747.203 | 0.3836 | 0.3603 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14747.203 | 0.0134 | -0.6470 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14747.203 | 0.0134 | -0.6470 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14747.203 | 0.0052 | -0.7585 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14747.203 | 0.0052 | -0.7585 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14747.203 | 0.0054 | -0.7544 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14747.203 | 0.0054 | -0.7544 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14747.203 | 0.0094 | -0.6934 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14747.203 | 0.0094 | -0.6934 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14747.203 | 0.0081 | -0.7124 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14747.203 | 0.0081 | -0.7124 | 2.4861 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15317.203 | 0.9489 | 0.9605 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15317.203 | 0.9489 | 0.9605 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15317.203 | 0.8597 | 0.8882 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15317.203 | 0.8597 | 0.8882 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15317.203 | 0.9251 | 0.9416 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15317.203 | 0.9251 | 0.9416 | 2.6269 | |
| MCF 10A | NM | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15317.203 | 0.8228 | 0.8569 | 2.6269 |