Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14909.203 | 0.0056 | -0.9537 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14909.203 | 0.0104 | -0.9270 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14909.203 | 0.0104 | -0.9270 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14909.203 | 0.0094 | -0.9320 | 1.3791 | |
| HCC38 | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14909.203 | 0.0094 | -0.9320 | 1.3791 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7470.074 | 0.9863 | 0.9716 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7470.074 | 0.9863 | 0.9716 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7470.074 | 0.9480 | 0.8921 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7470.074 | 0.9480 | 0.8921 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7470.074 | 0.8138 | 0.6143 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7470.074 | 0.8138 | 0.6143 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7470.074 | 0.0193 | -0.9671 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7470.074 | 0.0193 | -0.9671 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7470.074 | 0.0096 | -0.9840 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7470.074 | 0.0096 | -0.9840 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7470.074 | 0.0064 | -0.9895 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7470.074 | 0.0064 | -0.9895 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7470.074 | 0.0069 | -0.9887 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7470.074 | 0.0069 | -0.9887 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7470.074 | 0.0087 | -0.9855 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7470.074 | 0.0087 | -0.9855 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7470.074 | 0.0106 | -0.9823 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 167 | uM | 7470.074 | 0.0106 | -0.9823 | 0.9618 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14739.203 | 0.9456 | 0.8433 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14739.203 | 0.9456 | 0.8433 | 0.6862 |