Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14739.203 | 0.8533 | 0.5871 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14739.203 | 0.8533 | 0.5871 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14739.203 | 0.1422 | -0.8834 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14739.203 | 0.1422 | -0.8834 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14739.203 | 0.0076 | -0.9984 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14739.203 | 0.0076 | -0.9984 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14739.203 | 0.0087 | -0.9980 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14739.203 | 0.0087 | -0.9980 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14739.203 | 0.0064 | -0.9987 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14739.203 | 0.0064 | -0.9987 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14739.203 | 0.0096 | -0.9977 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14739.203 | 0.0096 | -0.9977 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14739.203 | 0.0131 | -0.9964 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14739.203 | 0.0131 | -0.9964 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14739.203 | 0.0109 | -0.9973 | 0.6862 | |
| HCC70 | TNBC | Basal A | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14739.203 | 0.0109 | -0.9973 | 0.6862 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7472.074 | 1.1084 | 1.1335 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7472.074 | 1.1084 | 1.1335 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7472.074 | 0.9747 | 0.9681 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7472.074 | 0.9747 | 0.9681 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7472.074 | 0.8241 | 0.7712 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7472.074 | 0.8241 | 0.7712 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7472.074 | 0.9732 | 0.9662 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7472.074 | 0.9732 | 0.9662 | 1.5922 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7472.074 | 0.0749 | -0.6072 | 1.5922 |