Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9024.075 | 0.9899 | 0.9930 | 2.8935 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9024.075 | 1.0459 | 1.0312 | 2.8935 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.16 | uM | 9024.075 | 1.0091 | 1.0063 | 2.8935 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9024.075 | 0.8018 | 0.8530 | 2.8935 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9024.075 | 0.2905 | 0.3047 | 2.8935 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9024.075 | 0.0118 | -0.5688 | 2.8935 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9024.075 | 0.0156 | -0.5248 | 2.8935 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 10261.011 | 0.9436 | 0.9528 | 2.4327 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 10261.011 | 1.0009 | 1.0008 | 2.4327 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 10261.011 | 0.9752 | 0.9794 | 2.4327 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 10261.011 | 0.9876 | 0.9898 | 2.4327 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 10261.011 | 0.9648 | 0.9708 | 2.4327 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 10261.011 | 0.7028 | 0.7301 | 2.4327 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 10261.011 | 0.2036 | 0.0397 | 2.4327 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 10261.011 | 0.0483 | -0.4246 | 2.4327 | |
| BT-549 | TNBC | Basal B | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 10261.011 | 0.0484 | -0.4239 | 2.4327 | |
| CAMA-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.00345 | uM | 9210.011 | 1.0115 | 1.0244 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0172 | uM | 9210.011 | 1.0059 | 1.0126 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.0862 | uM | 9210.011 | 1.0522 | 1.1108 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 0.431 | uM | 9210.011 | 0.9841 | 0.9664 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 2.15 | uM | 9210.011 | 1.0273 | 1.0579 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 10.8 | uM | 9210.011 | 0.9703 | 0.9371 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 53.9 | uM | 9210.011 | 0.8928 | 0.7737 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 269 | uM | 9210.011 | 0.6821 | 0.3336 | 0.9440 | |
| CAMA-1 | HR+ | Luminal | Carboplatin | DNA cross-linker | DNA cross-linker | 1350 | uM | 9210.011 | 0.0423 | -0.9298 | 0.9440 |