Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7443.074 | 0.4868 | -0.1213 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7443.074 | 0.3797 | -0.3384 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7443.074 | 0.3797 | -0.3384 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7443.074 | 0.3176 | -0.4605 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7443.074 | 0.3176 | -0.4605 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7444.074 | 0.9724 | 0.9277 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7444.074 | 0.9724 | 0.9277 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7444.074 | 0.9891 | 0.9713 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7444.074 | 0.9891 | 0.9713 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7444.074 | 1.0229 | 1.0604 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7444.074 | 1.0229 | 1.0604 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7444.074 | 1.0515 | 1.1365 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7444.074 | 1.0515 | 1.1365 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7444.074 | 0.7942 | 0.4770 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7444.074 | 0.7942 | 0.4770 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7444.074 | 0.5442 | -0.1017 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7444.074 | 0.5442 | -0.1017 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7444.074 | 0.4184 | -0.3643 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7444.074 | 0.4184 | -0.3643 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7444.074 | 0.2803 | -0.6247 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7444.074 | 0.2803 | -0.6247 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7444.074 | 0.2268 | -0.7159 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7444.074 | 0.2268 | -0.7159 | 0.7602 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14833.203 | 1.0143 | 1.0391 | 0.7338 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 14833.203 | 1.0143 | 1.0391 | 0.7338 |