Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7442.074 | 0.9804 | 0.9518 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7442.074 | 0.9804 | 0.9518 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7442.074 | 0.6288 | 0.1314 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7442.074 | 0.6288 | 0.1314 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7442.074 | 0.3811 | -0.3884 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7442.074 | 0.3811 | -0.3884 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7442.074 | 0.2985 | -0.5470 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7442.074 | 0.2985 | -0.5470 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7442.074 | 0.2195 | -0.6894 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7442.074 | 0.2195 | -0.6894 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7442.074 | 0.1309 | -0.8354 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 167 | uM | 7442.074 | 0.1309 | -0.8354 | 0.8143 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7443.074 | 0.9936 | 0.9854 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000427 | uM | 7443.074 | 0.9936 | 0.9854 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7443.074 | 0.9932 | 0.9845 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00213 | uM | 7443.074 | 0.9932 | 0.9845 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7443.074 | 0.9913 | 0.9802 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7443.074 | 0.9913 | 0.9802 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7443.074 | 1.0272 | 1.0623 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7443.074 | 1.0272 | 1.0623 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7443.074 | 0.8332 | 0.6236 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7443.074 | 0.8332 | 0.6236 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7443.074 | 0.6150 | 0.1477 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7443.074 | 0.6150 | 0.1477 | 0.8753 | |
| HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7443.074 | 0.4868 | -0.1213 | 0.8753 |