Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14833.203 | 1.0132 | 1.0359 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 14833.203 | 1.0132 | 1.0359 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14833.203 | 1.0114 | 1.0311 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 14833.203 | 1.0114 | 1.0311 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14833.203 | 0.6948 | 0.2176 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 14833.203 | 0.6948 | 0.2176 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14833.203 | 0.5574 | -0.0981 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 14833.203 | 0.5574 | -0.0981 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14833.203 | 0.4810 | -0.2622 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 14833.203 | 0.4810 | -0.2622 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14833.203 | 0.4244 | -0.3780 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 2.67 | uM | 14833.203 | 0.4244 | -0.3780 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14833.203 | 0.2967 | -0.6181 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 13.3 | uM | 14833.203 | 0.2967 | -0.6181 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14833.203 | 0.2609 | -0.6795 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 66.7 | uM | 14833.203 | 0.2609 | -0.6795 | 0.7338 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15304.203 | 0.9706 | 0.9215 | 0.7449 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15304.203 | 0.9706 | 0.9215 | 0.7449 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15304.203 | 0.9258 | 0.8034 | 0.7449 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15304.203 | 0.9258 | 0.8034 | 0.7449 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15304.203 | 0.8355 | 0.5712 | 0.7449 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15304.203 | 0.8355 | 0.5712 | 0.7449 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15304.203 | 0.3577 | -0.4969 | 0.7449 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15304.203 | 0.3577 | -0.4969 | 0.7449 | |
HCC1428 | HR+ | Luminal | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15304.203 | 0.4133 | -0.3892 | 0.7449 |