Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 11057.151 | 0.0855 | 0.1090 | 4.1698 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 11057.151 | 0.2521 | 0.4371 | 4.1698 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 11057.151 | 0.1019 | 0.1565 | 4.1698 | |
| SUM185PE | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12269.157 | 1.3760 | 2.6129 | 0.5397 | |
| SUM185PE | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12269.157 | 1.2927 | 2.2183 | 0.5397 | |
| SUM185PE | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12269.157 | 1.3575 | 2.5234 | 0.5397 | |
| SUM185PE | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12269.157 | 0.6451 | -0.1124 | 0.5397 | |
| SUM185PE | TNBC | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12269.157 | 0.9901 | 0.9635 | 0.5397 | |
| SUM185PE | TNBC | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12269.157 | 0.7382 | 0.1397 | 0.5397 | |
| SUM185PE | TNBC | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12269.157 | 0.7479 | 0.1676 | 0.5397 | |
| SUM185PE | TNBC | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12269.157 | 0.7632 | 0.2122 | 0.5397 | |
| SUM185PE | TNBC | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12269.157 | 0.7390 | 0.1418 | 0.5397 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10579.139 | 1.0416 | 1.0737 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10579.139 | 0.9638 | 0.9355 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10579.139 | 0.9440 | 0.9003 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10579.139 | 1.0057 | 1.0101 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.213 | uM | 10579.139 | 0.9430 | 0.8985 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 1.07 | uM | 10579.139 | 0.9172 | 0.8521 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 5.33 | uM | 10579.139 | 0.5470 | 0.1704 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 26.7 | uM | 10579.139 | 0.5246 | 0.1277 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 133 | uM | 10579.139 | 0.5415 | 0.1599 | 1.1260 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12098.157 | 0.9863 | 0.9790 | 1.3067 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12098.157 | 1.0989 | 1.1497 | 1.3067 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12098.157 | 0.9258 | 0.8853 | 1.3067 | |
| SUM225CWN | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12098.157 | 1.0228 | 1.0348 | 1.3067 |