Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 10819.151 | 0.3610 | 0.2371 | 2.1209 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11937.157 | 1.0629 | 1.0514 | 2.4025 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11937.157 | 0.9877 | 0.9897 | 2.4025 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11937.157 | 0.9690 | 0.9739 | 2.4025 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11937.157 | 1.0003 | 1.0002 | 2.4025 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 11937.157 | 0.9896 | 0.9913 | 2.4025 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 11937.157 | 0.8059 | 0.8281 | 2.4025 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 11937.157 | 0.1888 | -0.0008 | 2.4025 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 11937.157 | 0.3867 | 0.3468 | 2.4025 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 11937.157 | 0.3891 | 0.3502 | 2.4025 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10520.139 | 0.9876 | 0.9932 | 3.6491 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10520.139 | 0.7329 | 0.8367 | 3.6491 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10520.139 | 0.8490 | 0.9122 | 3.6491 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10520.139 | 1.0572 | 1.0307 | 3.6491 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 10520.139 | 0.8201 | 0.8942 | 3.6491 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 10520.139 | 0.1616 | 0.2137 | 3.6491 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 10520.139 | 0.0126 | -0.3973 | 3.6491 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 10520.139 | 0.0403 | -0.1706 | 3.6491 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 10520.139 | 0.0009 | -0.7104 | 3.6491 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11057.151 | 1.0082 | 1.0039 | 4.1698 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11057.151 | 0.9845 | 0.9925 | 4.1698 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11057.151 | 1.0199 | 1.0095 | 4.1698 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11057.151 | 0.9681 | 0.9845 | 4.1698 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 11057.151 | 0.9572 | 0.9791 | 4.1698 | |
| SUM159PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 11057.151 | 0.2428 | 0.4243 | 4.1698 |