Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10875.151 | 0.9793 | 0.9419 | 0.7096 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10875.151 | 0.9927 | 0.9795 | 0.7096 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10875.151 | 0.9953 | 0.9869 | 0.7096 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 10875.151 | 0.9573 | 0.8808 | 0.7096 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 10875.151 | 0.3998 | -0.4506 | 0.7096 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 10875.151 | 0.1546 | -0.8560 | 0.7096 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 10875.151 | 0.1166 | -0.9033 | 0.7096 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 10875.151 | 0.1368 | -0.8788 | 0.7096 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12428.157 | 1.0172 | 1.0349 | 0.9842 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12428.157 | 0.9953 | 0.9904 | 0.9842 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12428.157 | 0.9998 | 0.9996 | 0.9842 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12428.157 | 0.9714 | 0.9418 | 0.9842 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 12428.157 | 1.0227 | 1.0461 | 0.9842 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 12428.157 | 0.7321 | 0.4568 | 0.9842 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 12428.157 | 0.3372 | -0.3372 | 0.9842 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 12428.157 | 0.6440 | 0.2789 | 0.9842 | |
| SUM1315MO2 | TNBC | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 12428.157 | 0.6835 | 0.3588 | 0.9842 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10819.151 | 1.0313 | 1.0293 | 2.1209 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10819.151 | 0.9683 | 0.9698 | 2.1209 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10819.151 | 1.0102 | 1.0096 | 2.1209 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10819.151 | 0.9574 | 0.9594 | 2.1209 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 10819.151 | 0.9998 | 0.9998 | 2.1209 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 10819.151 | 0.5396 | 0.4952 | 2.1209 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 10819.151 | 0.4130 | 0.3181 | 2.1209 | |
| SUM149PT | TNBC | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 10819.151 | 0.3008 | 0.1352 | 2.1209 |