Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MB 157 | Unknown | Unknown | XRP44X | ELK3 | MAPK | 133 | uM | 12580.171 | 0.2417 | -0.0074 | 2.0272 | |
| MCF 10A | NM | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11056.151 | 0.9564 | 0.9708 | 3.0292 | |
| MCF 10A | NM | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11056.151 | 0.9949 | 0.9966 | 3.0292 | |
| MCF 10A | NM | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11056.151 | 1.0052 | 1.0034 | 3.0292 | |
| MCF 10A | NM | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11056.151 | 1.0266 | 1.0174 | 3.0292 | |
| MCF 10A | NM | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 11056.151 | 0.8939 | 0.9273 | 3.0292 | |
| MCF 10A | NM | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 11056.151 | 0.1385 | 0.0414 | 3.0292 | |
| MCF 10A | NM | Basal B | XRP44X | ELK3 | MAPK | 5.33 | uM | 11056.151 | 0.1402 | 0.0456 | 3.0292 | |
| MCF 10A | NM | Basal B | XRP44X | ELK3 | MAPK | 26.7 | uM | 11056.151 | 0.1303 | 0.0205 | 3.0292 | |
| MCF 10A | NM | Basal B | XRP44X | ELK3 | MAPK | 133 | uM | 11056.151 | 0.1482 | 0.0648 | 3.0292 | |
| MCF 10F | NM | - | XRP44X | ELK3 | MAPK | 0.000341 | uM | 12254.157 | 1.0572 | 1.0667 | 1.6969 | |
| MCF 10F | NM | - | XRP44X | ELK3 | MAPK | 0.00171 | uM | 12254.157 | 1.0194 | 1.0228 | 1.6969 | |
| MCF 10F | NM | - | XRP44X | ELK3 | MAPK | 0.00853 | uM | 12254.157 | 1.1079 | 1.1245 | 1.6969 | |
| MCF 10F | NM | - | XRP44X | ELK3 | MAPK | 0.0427 | uM | 12254.157 | 1.0965 | 1.1116 | 1.6969 | |
| MCF 10F | NM | - | XRP44X | ELK3 | MAPK | 0.213 | uM | 12254.157 | 0.9932 | 0.9919 | 1.6969 | |
| MCF 10F | NM | - | XRP44X | ELK3 | MAPK | 1.07 | uM | 12254.157 | 0.9304 | 0.9168 | 1.6969 | |
| MCF 10F | NM | - | XRP44X | ELK3 | MAPK | 5.33 | uM | 12254.157 | 0.8723 | 0.8453 | 1.6969 | |
| MCF 10F | NM | - | XRP44X | ELK3 | MAPK | 26.7 | uM | 12254.157 | 0.7859 | 0.7352 | 1.6969 | |
| MCF 10F | NM | - | XRP44X | ELK3 | MAPK | 133 | uM | 12254.157 | 0.8262 | 0.7872 | 1.6969 | |
| MCF12A | NM | Basal B | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10817.151 | 1.0011 | 1.0015 | 1.4848 | |
| MCF12A | NM | Basal B | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10817.151 | 1.0037 | 1.0049 | 1.4848 | |
| MCF12A | NM | Basal B | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10817.151 | 1.0221 | 1.0296 | 1.4848 | |
| MCF12A | NM | Basal B | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10817.151 | 0.9992 | 0.9990 | 1.4848 | |
| MCF12A | NM | Basal B | XRP44X | ELK3 | MAPK | 0.213 | uM | 10817.151 | 0.7453 | 0.6408 | 1.4848 | |
| MCF12A | NM | Basal B | XRP44X | ELK3 | MAPK | 1.07 | uM | 10817.151 | 0.2728 | -0.1662 | 1.4848 |