Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.96 | uM | 10875.143 | 0.9858 | 0.9656 | 0.8219 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 4.8 | uM | 10875.143 | 0.9772 | 0.9447 | 0.8219 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 24 | uM | 10875.143 | 0.9846 | 0.9627 | 0.8219 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 120 | uM | 10875.143 | 0.9947 | 0.9870 | 0.8219 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 600 | uM | 10875.143 | 0.9761 | 0.9420 | 0.8219 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 3000 | uM | 10875.143 | 0.6070 | 0.0895 | 0.8219 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 15000 | uM | 10875.143 | 0.1372 | -0.8216 | 0.8219 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.0384 | uM | 12428.143 | 1.0363 | 1.1036 | 0.7057 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.192 | uM | 12428.143 | 1.0580 | 1.1662 | 0.7057 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.96 | uM | 12428.143 | 1.0559 | 1.1602 | 0.7057 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 4.8 | uM | 12428.143 | 1.0833 | 1.2401 | 0.7057 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 24 | uM | 12428.143 | 1.0265 | 1.0754 | 0.7057 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 120 | uM | 12428.143 | 1.0611 | 1.1754 | 0.7057 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 600 | uM | 12428.143 | 1.0791 | 1.2279 | 0.7057 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 3000 | uM | 12428.143 | 0.6786 | 0.1546 | 0.7057 | |
| SUM1315MO2 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 15000 | uM | 12428.143 | 0.1770 | -0.8280 | 0.7057 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.0384 | uM | 10819.143 | 0.9660 | 0.9696 | 2.2570 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.192 | uM | 10819.143 | 0.8941 | 0.9032 | 2.2570 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.96 | uM | 10819.143 | 0.9378 | 0.9439 | 2.2570 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 4.8 | uM | 10819.143 | 0.8933 | 0.9024 | 2.2570 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 24 | uM | 10819.143 | 0.9528 | 0.9576 | 2.2570 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 120 | uM | 10819.143 | 0.9360 | 0.9422 | 2.2570 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 600 | uM | 10819.143 | 0.7360 | 0.7460 | 2.2570 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 3000 | uM | 10819.143 | 0.3407 | 0.2412 | 2.2570 | |
| SUM149PT | TNBC | Basal B | Valproic acid | HDAC | HDAC | 15000 | uM | 10819.143 | 0.0188 | -0.6559 | 2.2570 |