Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset - HMS LINCS Database

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Small molecules	Cells	Antibodies

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Cell	Clinical Subtype	Transcriptional Subtype	Small Molecule	Perturbagen Target	Perturbagen Class	Perturbagen Concentration	Perturbagen Conc Unit	Biological Replicate ID	Relative Cell Count	Normalized Growth Rate Inhibition Value	Nominal Division Rate
MDA-MB-175-VII	HR+	Luminal	XRP44X	ELK3	MAPK	0.000341	uM	12126.157	0.9196	0.7901	0.7555
MDA-MB-175-VII	HR+	Luminal	XRP44X	ELK3	MAPK	0.00171	uM	12126.157	0.9096	0.7642	0.7555
MDA-MB-175-VII	HR+	Luminal	XRP44X	ELK3	MAPK	0.00853	uM	12126.157	0.9873	0.9666	0.7555
MDA-MB-175-VII	HR+	Luminal	XRP44X	ELK3	MAPK	0.0427	uM	12126.157	0.9678	0.9152	0.7555
MDA-MB-175-VII	HR+	Luminal	XRP44X	ELK3	MAPK	0.213	uM	12126.157	0.9032	0.7480	0.7555
MDA-MB-175-VII	HR+	Luminal	XRP44X	ELK3	MAPK	1.07	uM	12126.157	0.9224	0.7971	0.7555
MDA-MB-175-VII	HR+	Luminal	XRP44X	ELK3	MAPK	5.33	uM	12126.157	0.6488	0.1281	0.7555
MDA-MB-175-VII	HR+	Luminal	XRP44X	ELK3	MAPK	26.7	uM	12126.157	0.6999	0.2472	0.7555
MDA-MB-175-VII	HR+	Luminal	XRP44X	ELK3	MAPK	133	uM	12126.157	0.8085	0.5096	0.7555
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	0.000341	uM	10643.139	1.0512	1.1623	0.6402
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	0.00171	uM	10643.139	1.0110	1.0344	0.6402
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	0.00853	uM	10643.139	1.0443	1.1400	0.6402
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	0.0427	uM	10643.139	1.0337	1.1064	0.6402
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	0.213	uM	10643.139	1.0342	1.1078	0.6402
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	1.07	uM	10643.139	0.8710	0.6120	0.6402
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	5.33	uM	10643.139	0.5668	-0.1763	0.6402
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	26.7	uM	10643.139	0.5374	-0.2419	0.6402
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	133	uM	10643.139	0.5312	-0.2555	0.6402
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	0.000341	uM	10999.151	0.9907	0.9739	0.7090
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	0.00171	uM	10999.151	1.0211	1.0597	0.7090
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	0.00853	uM	10999.151	0.9849	0.9576	0.7090
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	0.0427	uM	10999.151	1.0152	1.0429	0.7090
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	0.213	uM	10999.151	0.9639	0.8990	0.7090
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	1.07	uM	10999.151	0.3702	-0.5076	0.7090
MDA-MB-361	HER2amp	Luminal	XRP44X	ELK3	MAPK	5.33	uM	10999.151	0.3797	-0.4896	0.7090

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HMS LINCS Project

Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)