Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-175-VII | HR+ | Luminal | Valproic acid | HDAC | HDAC | 0.192 | uM | 12126.143 | 0.9073 | 0.7307 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | Valproic acid | HDAC | HDAC | 0.96 | uM | 12126.143 | 0.9565 | 0.8720 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | Valproic acid | HDAC | HDAC | 4.8 | uM | 12126.143 | 0.9018 | 0.7152 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | Valproic acid | HDAC | HDAC | 24 | uM | 12126.143 | 0.9000 | 0.7103 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | Valproic acid | HDAC | HDAC | 120 | uM | 12126.143 | 0.9615 | 0.8867 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | Valproic acid | HDAC | HDAC | 600 | uM | 12126.143 | 0.8831 | 0.6627 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | Valproic acid | HDAC | HDAC | 3000 | uM | 12126.143 | 0.7143 | 0.2131 | 0.6729 | |
| MDA-MB-175-VII | HR+ | Luminal | Valproic acid | HDAC | HDAC | 15000 | uM | 12126.143 | 0.0257 | -0.9913 | 0.6729 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 0.0384 | uM | 10643.143 | 0.9923 | 0.9684 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 0.192 | uM | 10643.143 | 1.0156 | 1.0645 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 0.96 | uM | 10643.143 | 0.9624 | 0.8484 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 4.8 | uM | 10643.143 | 0.9635 | 0.8528 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 24 | uM | 10643.143 | 0.9798 | 0.9179 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 120 | uM | 10643.143 | 1.0122 | 1.0505 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 600 | uM | 10643.143 | 0.9259 | 0.7072 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 3000 | uM | 10643.143 | 0.6892 | -0.0692 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 15000 | uM | 10643.143 | 0.0259 | -0.9989 | 0.4866 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 0.0384 | uM | 10999.143 | 1.0299 | 1.1163 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 0.192 | uM | 10999.143 | 0.9779 | 0.9162 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 0.96 | uM | 10999.143 | 1.0159 | 1.0613 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 4.8 | uM | 10999.143 | 1.0228 | 1.0882 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 24 | uM | 10999.143 | 1.0029 | 1.0111 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 120 | uM | 10999.143 | 1.0504 | 1.1978 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 600 | uM | 10999.143 | 0.9790 | 0.9202 | 0.5216 | |
| MDA-MB-361 | HER2amp | Luminal | Valproic acid | HDAC | HDAC | 3000 | uM | 10999.143 | 0.6861 | -0.0287 | 0.5216 |