Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 600 | uM | 10577.143 | 1.0069 | 1.0141 | 0.9750 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 3000 | uM | 10577.143 | 0.6280 | 0.2411 | 0.9750 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 15000 | uM | 10577.143 | 0.0934 | -0.8241 | 0.9750 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 0.0384 | uM | 10937.143 | 1.0862 | 1.1300 | 1.3133 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 0.192 | uM | 10937.143 | 1.0268 | 1.0407 | 1.3133 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 0.96 | uM | 10937.143 | 1.0085 | 1.0129 | 1.3133 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 4.8 | uM | 10937.143 | 0.9789 | 0.9677 | 1.3133 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 24 | uM | 10937.143 | 0.9547 | 0.9307 | 1.3133 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 120 | uM | 10937.143 | 1.0391 | 1.0592 | 1.3133 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 600 | uM | 10937.143 | 0.9831 | 0.9741 | 1.3133 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 3000 | uM | 10937.143 | 0.6748 | 0.4823 | 1.3133 | |
| HCC3153 | TNBC | Basal A | Valproic acid | HDAC | HDAC | 15000 | uM | 10937.143 | 0.1086 | -0.6312 | 1.3133 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.0384 | uM | 10578.143 | 1.0081 | 1.0096 | 1.6935 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.192 | uM | 10578.143 | 0.9671 | 0.9608 | 1.6935 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.96 | uM | 10578.143 | 0.9416 | 0.9301 | 1.6935 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 4.8 | uM | 10578.143 | 0.9610 | 0.9536 | 1.6935 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 24 | uM | 10578.143 | 0.9414 | 0.9299 | 1.6935 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 120 | uM | 10578.143 | 0.9139 | 0.8964 | 1.6935 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 600 | uM | 10578.143 | 0.7501 | 0.6877 | 1.6935 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 3000 | uM | 10578.143 | 0.2534 | -0.1109 | 1.6935 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 15000 | uM | 10578.143 | 0.0070 | -0.8934 | 1.6935 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.0384 | uM | 11850.143 | 0.9152 | 0.9175 | 2.1044 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.192 | uM | 11850.143 | 1.0020 | 1.0019 | 2.1044 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 0.96 | uM | 11850.143 | 1.0035 | 1.0033 | 2.1044 | |
| HCC38 | TNBC | Basal B | Valproic acid | HDAC | HDAC | 4.8 | uM | 11850.143 | 1.0175 | 1.0165 | 2.1044 |