Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1419 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 12001.157 | 0.9416 | 0.8062 | 0.5904 | |
| HCC1419 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 12001.157 | 0.9658 | 0.8856 | 0.5904 | |
| HCC1419 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 12001.157 | 0.8443 | 0.5016 | 0.5904 | |
| HCC1419 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 12001.157 | 0.8390 | 0.4856 | 0.5904 | |
| HCC1419 | HER2amp | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 12001.157 | 0.8920 | 0.6482 | 0.5904 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10693.151 | 1.0212 | 1.0448 | 0.9475 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10693.151 | 0.9376 | 0.8686 | 0.9475 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 10693.151 | 0.9849 | 0.9681 | 0.9475 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 10693.151 | 0.9613 | 0.9185 | 0.9475 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 10693.151 | 1.0007 | 1.0014 | 0.9475 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 10693.151 | 0.8252 | 0.6328 | 0.9475 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 10693.151 | 0.7068 | 0.3867 | 0.9475 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 10693.151 | 0.6975 | 0.3675 | 0.9475 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 10693.151 | 0.7046 | 0.3822 | 0.9475 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.000341 | uM | 11936.157 | 0.9437 | 0.8771 | 0.9133 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00171 | uM | 11936.157 | 0.9507 | 0.8924 | 0.9133 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.00853 | uM | 11936.157 | 0.9060 | 0.7950 | 0.9133 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.0427 | uM | 11936.157 | 0.9538 | 0.8991 | 0.9133 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 0.213 | uM | 11936.157 | 0.9456 | 0.8812 | 0.9133 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 1.07 | uM | 11936.157 | 0.8602 | 0.6959 | 0.9133 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 5.33 | uM | 11936.157 | 0.5694 | 0.0796 | 0.9133 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 26.7 | uM | 11936.157 | 0.6637 | 0.2767 | 0.9133 | |
| HCC1428 | HR+ | Luminal | XRP44X | ELK3 | MAPK | 133 | uM | 11936.157 | 0.6600 | 0.2690 | 0.9133 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.000341 | uM | 10872.151 | 1.0044 | 1.0063 | 1.4028 | |
| HCC1569 | HER2amp | Basal A | XRP44X | ELK3 | MAPK | 0.00171 | uM | 10872.151 | 1.0408 | 1.0578 | 1.4028 |