Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 6.67 | uM | 10875.153 | 0.9601 | 0.9059 | 0.8455 | |
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 33.3 | uM | 10875.153 | 0.6005 | 0.0941 | 0.8455 | |
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 12428.165 | 1.0035 | 1.0100 | 0.7051 | |
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000427 | uM | 12428.165 | 0.9897 | 0.9709 | 0.7051 | |
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.00213 | uM | 12428.165 | 1.0085 | 1.0241 | 0.7051 | |
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0107 | uM | 12428.165 | 0.9960 | 0.9887 | 0.7051 | |
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0533 | uM | 12428.165 | 1.0080 | 1.0228 | 0.7051 | |
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.267 | uM | 12428.165 | 1.0521 | 1.1495 | 0.7051 | |
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 1.33 | uM | 12428.165 | 1.0198 | 1.0564 | 0.7051 | |
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 6.67 | uM | 12428.165 | 0.9137 | 0.7596 | 0.7051 | |
| SUM1315MO2 | TNBC | Basal B | AS-252424 | PI3K | PI3K | 33.3 | uM | 12428.165 | 0.6450 | 0.0739 | 0.7051 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 10819.153 | 0.9879 | 0.9883 | 2.0690 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000427 | uM | 10819.153 | 0.9594 | 0.9603 | 2.0690 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.00213 | uM | 10819.153 | 0.9679 | 0.9687 | 2.0690 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0107 | uM | 10819.153 | 1.0062 | 1.0060 | 2.0690 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0533 | uM | 10819.153 | 1.0372 | 1.0356 | 2.0690 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.267 | uM | 10819.153 | 0.9877 | 0.9881 | 2.0690 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 1.33 | uM | 10819.153 | 1.0868 | 1.0821 | 2.0690 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 6.67 | uM | 10819.153 | 0.7928 | 0.7877 | 2.0690 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 33.3 | uM | 10819.153 | 0.6827 | 0.6630 | 2.0690 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000171 | uM | 11937.158 | 1.0020 | 1.0018 | 2.2386 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.000853 | uM | 11937.158 | 0.9586 | 0.9626 | 2.2386 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.00427 | uM | 11937.158 | 1.0125 | 1.0111 | 2.2386 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.0213 | uM | 11937.158 | 1.0065 | 1.0058 | 2.2386 | |
| SUM149PT | TNBC | Basal B | AS-252424 | PI3K | PI3K | 0.107 | uM | 11937.158 | 1.0869 | 1.0758 | 2.2386 |