Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0107 | uM | 7475.074 | 1.1185 | 1.0924 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7475.074 | 0.9486 | 0.9579 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0533 | uM | 7475.074 | 0.9486 | 0.9579 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7475.074 | 0.0043 | -0.7783 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.267 | uM | 7475.074 | 0.0043 | -0.7783 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7475.074 | 0.0043 | -0.7783 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 1.33 | uM | 7475.074 | 0.0043 | -0.7783 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7475.074 | 0.0025 | -0.8216 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 6.67 | uM | 7475.074 | 0.0025 | -0.8216 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7475.074 | 0.0086 | -0.7068 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 33.3 | uM | 7475.074 | 0.0086 | -0.7068 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7475.074 | 0.0011 | -0.8733 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 167 | uM | 7475.074 | 0.0011 | -0.8733 | 2.4793 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15310.203 | 0.9379 | 0.9487 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000171 | uM | 15310.203 | 0.9379 | 0.9487 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15310.203 | 0.8302 | 0.8547 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.000853 | uM | 15310.203 | 0.8302 | 0.8547 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15310.203 | 0.8260 | 0.8510 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.00427 | uM | 15310.203 | 0.8260 | 0.8510 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15310.203 | 0.1644 | -0.0377 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.0213 | uM | 15310.203 | 0.1644 | -0.0377 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15310.203 | 0.0194 | -0.5955 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.107 | uM | 15310.203 | 0.0194 | -0.5955 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15310.203 | 0.0151 | -0.6341 | 2.4683 | |
| Hs 578T | TNBC | Basal B | Bortezomib | Proteasome | Proteasome | 0.533 | uM | 15310.203 | 0.0151 | -0.6341 | 2.4683 |