Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | NM | Basal B | AS-252424 | PI3K | PI3K | 0.533 | uM | 11056.158 | 1.0664 | 1.0475 | 2.7355 | |
| MCF 10A | NM | Basal B | AS-252424 | PI3K | PI3K | 2.67 | uM | 11056.158 | 0.8338 | 0.8714 | 2.7355 | |
| MCF 10A | NM | Basal B | AS-252424 | PI3K | PI3K | 13.3 | uM | 11056.158 | 0.3732 | 0.3950 | 2.7355 | |
| MCF 10A | NM | Basal B | AS-252424 | PI3K | PI3K | 66.7 | uM | 11056.158 | 1.0410 | 1.0296 | 2.7355 | |
| MCF 10F | NM | - | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 12254.165 | 0.9933 | 0.9921 | 1.6980 | |
| MCF 10F | NM | - | AS-252424 | PI3K | PI3K | 0.000427 | uM | 12254.165 | 1.0459 | 1.0536 | 1.6980 | |
| MCF 10F | NM | - | AS-252424 | PI3K | PI3K | 0.00213 | uM | 12254.165 | 0.9987 | 0.9984 | 1.6980 | |
| MCF 10F | NM | - | AS-252424 | PI3K | PI3K | 0.0107 | uM | 12254.165 | 1.0221 | 1.0260 | 1.6980 | |
| MCF 10F | NM | - | AS-252424 | PI3K | PI3K | 0.0533 | uM | 12254.165 | 1.0824 | 1.0955 | 1.6980 | |
| MCF 10F | NM | - | AS-252424 | PI3K | PI3K | 0.267 | uM | 12254.165 | 1.2217 | 1.2503 | 1.6980 | |
| MCF 10F | NM | - | AS-252424 | PI3K | PI3K | 1.33 | uM | 12254.165 | 1.2941 | 1.3279 | 1.6980 | |
| MCF 10F | NM | - | AS-252424 | PI3K | PI3K | 6.67 | uM | 12254.165 | 0.8494 | 0.8167 | 1.6980 | |
| MCF 10F | NM | - | AS-252424 | PI3K | PI3K | 33.3 | uM | 12254.165 | 0.6587 | 0.5640 | 1.6980 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 10817.153 | 1.0360 | 1.0427 | 1.6726 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 0.000427 | uM | 10817.153 | 0.9488 | 0.9381 | 1.6726 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 0.00213 | uM | 10817.153 | 0.9775 | 0.9730 | 1.6726 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 0.0107 | uM | 10817.153 | 0.9587 | 0.9502 | 1.6726 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 0.0533 | uM | 10817.153 | 0.9850 | 0.9821 | 1.6726 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 0.267 | uM | 10817.153 | 0.9056 | 0.8848 | 1.6726 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 1.33 | uM | 10817.153 | 0.9575 | 0.9488 | 1.6726 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 6.67 | uM | 10817.153 | 0.7946 | 0.7431 | 1.6726 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 33.3 | uM | 10817.153 | 0.5760 | 0.4381 | 1.6726 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 0.0000853 | uM | 12365.165 | 0.9893 | 0.9888 | 1.9114 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 0.000427 | uM | 12365.165 | 1.0141 | 1.0147 | 1.9114 | |
| MCF12A | NM | Basal B | AS-252424 | PI3K | PI3K | 0.00213 | uM | 12365.165 | 1.0034 | 1.0035 | 1.9114 |