Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
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MCF 10A | NM | Basal B | PD 98059 | MEK | MAPK | 0.00064 | uM | 11056.152 | 1.0071 | 1.0048 | 2.9748 | |
MCF 10A | NM | Basal B | PD 98059 | MEK | MAPK | 0.0032 | uM | 11056.152 | 0.9372 | 0.9569 | 2.9748 | |
MCF 10A | NM | Basal B | PD 98059 | MEK | MAPK | 0.016 | uM | 11056.152 | 0.9636 | 0.9752 | 2.9748 | |
MCF 10A | NM | Basal B | PD 98059 | MEK | MAPK | 0.08 | uM | 11056.152 | 0.9802 | 0.9866 | 2.9748 | |
MCF 10A | NM | Basal B | PD 98059 | MEK | MAPK | 0.4 | uM | 11056.152 | 0.9522 | 0.9673 | 2.9748 | |
MCF 10A | NM | Basal B | PD 98059 | MEK | MAPK | 2 | uM | 11056.152 | 0.9576 | 0.9711 | 2.9748 | |
MCF 10A | NM | Basal B | PD 98059 | MEK | MAPK | 10 | uM | 11056.152 | 0.8870 | 0.9210 | 2.9748 | |
MCF 10A | NM | Basal B | PD 98059 | MEK | MAPK | 50 | uM | 11056.152 | 0.7387 | 0.8064 | 2.9748 | |
MCF 10F | NM | - | PD 98059 | MEK | MAPK | 0.000128 | uM | 12254.152 | 0.9414 | 0.9354 | 1.8382 | |
MCF 10F | NM | - | PD 98059 | MEK | MAPK | 0.00064 | uM | 12254.152 | 0.9464 | 0.9410 | 1.8382 | |
MCF 10F | NM | - | PD 98059 | MEK | MAPK | 0.0032 | uM | 12254.152 | 1.0100 | 1.0109 | 1.8382 | |
MCF 10F | NM | - | PD 98059 | MEK | MAPK | 0.016 | uM | 12254.152 | 0.9748 | 0.9724 | 1.8382 | |
MCF 10F | NM | - | PD 98059 | MEK | MAPK | 0.08 | uM | 12254.152 | 0.9707 | 0.9679 | 1.8382 | |
MCF 10F | NM | - | PD 98059 | MEK | MAPK | 0.4 | uM | 12254.152 | 1.0117 | 1.0127 | 1.8382 | |
MCF 10F | NM | - | PD 98059 | MEK | MAPK | 2 | uM | 12254.152 | 1.1402 | 1.1479 | 1.8382 | |
MCF 10F | NM | - | PD 98059 | MEK | MAPK | 10 | uM | 12254.152 | 1.1787 | 1.1872 | 1.8382 | |
MCF 10F | NM | - | PD 98059 | MEK | MAPK | 50 | uM | 12254.152 | 0.9219 | 0.9135 | 1.8382 | |
MCF12A | NM | Basal B | PD 98059 | MEK | MAPK | 0.000128 | uM | 10817.152 | 0.9772 | 0.9682 | 1.4414 | |
MCF12A | NM | Basal B | PD 98059 | MEK | MAPK | 0.00064 | uM | 10817.152 | 0.9898 | 0.9859 | 1.4414 | |
MCF12A | NM | Basal B | PD 98059 | MEK | MAPK | 0.0032 | uM | 10817.152 | 0.9590 | 0.9427 | 1.4414 | |
MCF12A | NM | Basal B | PD 98059 | MEK | MAPK | 0.016 | uM | 10817.152 | 0.9892 | 0.9851 | 1.4414 | |
MCF12A | NM | Basal B | PD 98059 | MEK | MAPK | 0.08 | uM | 10817.152 | 1.0000 | 1.0000 | 1.4414 | |
MCF12A | NM | Basal B | PD 98059 | MEK | MAPK | 0.4 | uM | 10817.152 | 0.9990 | 0.9986 | 1.4414 | |
MCF12A | NM | Basal B | PD 98059 | MEK | MAPK | 2 | uM | 10817.152 | 0.9537 | 0.9353 | 1.4414 | |
MCF12A | NM | Basal B | PD 98059 | MEK | MAPK | 10 | uM | 10817.152 | 0.8928 | 0.8486 | 1.4414 |