Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)

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Cell Clinical Subtype Transcriptional Subtype Small Molecule Antibody Perturbagen Target Perturbagen Class Perturbagen Concentration Perturbagen Conc Unit Biological Replicate ID Relative Cell Count Normalized Growth Rate Inhibition Value Nominal Division Rate
MCF12A
NM
Basal B
 PD 98059
MEK
MAPK
50
uM
10817.152
 0.8266 0.7524 1.4414
MCF12A
NM
Basal B
 PD 98059
MEK
MAPK
0.000128
uM
12365.152
 0.9786 0.9796 2.1145
MCF12A
NM
Basal B
 PD 98059
MEK
MAPK
0.00064
uM
12365.152
 1.0272 1.0256 2.1145
MCF12A
NM
Basal B
 PD 98059
MEK
MAPK
0.0032
uM
12365.152
 1.0193 1.0181 2.1145
MCF12A
NM
Basal B
 PD 98059
MEK
MAPK
0.016
uM
12365.152
 0.9783 0.9793 2.1145
MCF12A
NM
Basal B
 PD 98059
MEK
MAPK
0.08
uM
12365.152
 1.0228 1.0214 2.1145
MCF12A
NM
Basal B
 PD 98059
MEK
MAPK
0.4
uM
12365.152
 1.0325 1.0305 2.1145
MCF12A
NM
Basal B
 PD 98059
MEK
MAPK
2
uM
12365.152
 0.9906 0.9911 2.1145
MCF12A
NM
Basal B
 PD 98059
MEK
MAPK
10
uM
12365.152
 1.0096 1.0090 2.1145
MCF12A
NM
Basal B
 PD 98059
MEK
MAPK
50
uM
12365.152
 0.8900 0.8928 2.1145
MCF7
HR+
Luminal
 PD 98059
MEK
MAPK
0.000128
uM
10997.152
 0.9407 0.9141 1.3917
MCF7
HR+
Luminal
 PD 98059
MEK
MAPK
0.00064
uM
10997.152
 0.9722 0.9599 1.3917
MCF7
HR+
Luminal
 PD 98059
MEK
MAPK
0.0032
uM
10997.152
 0.9415 0.9152 1.3917
MCF7
HR+
Luminal
 PD 98059
MEK
MAPK
0.016
uM
10997.152
 0.9626 0.9459 1.3917
MCF7
HR+
Luminal
 PD 98059
MEK
MAPK
0.08
uM
10997.152
 0.9834 0.9761 1.3917
MCF7
HR+
Luminal
 PD 98059
MEK
MAPK
0.4
uM
10997.152
 0.9617 0.9446 1.3917
MCF7
HR+
Luminal
 PD 98059
MEK
MAPK
2
uM
10997.152
 1.0066 1.0095 1.3917
MCF7
HR+
Luminal
 PD 98059
MEK
MAPK
10
uM
10997.152
 0.9807 0.9722 1.3917
MCF7
HR+
Luminal
 PD 98059
MEK
MAPK
50
uM
10997.152
 0.9766 0.9662 1.3917
MDA-MB-134-VI
HR+
Luminal
 PD 98059
MEK
MAPK
0.000256
uM
10519.136
 1.0083 1.0146 1.1406
MDA-MB-134-VI
HR+
Luminal
 PD 98059
MEK
MAPK
0.00128
uM
10519.136
 0.9709 0.9488 1.1406
MDA-MB-134-VI
HR+
Luminal
 PD 98059
MEK
MAPK
0.0064
uM
10519.136
 1.0362 1.0634 1.1406
MDA-MB-134-VI
HR+
Luminal
 PD 98059
MEK
MAPK
0.032
uM
10519.136
 1.0065 1.0114 1.1406
MDA-MB-134-VI
HR+
Luminal
 PD 98059
MEK
MAPK
0.16
uM
10519.136
 0.9734 0.9533 1.1406
MDA-MB-134-VI
HR+
Luminal
 PD 98059
MEK
MAPK
0.8
uM
10519.136
 1.0098 1.0171 1.1406