Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10267.011 | 0.6865 | -0.2982 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10267.011 | 0.1799 | -0.9831 | 0.3592 | |
| UACC-812 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10267.011 | 0.0681 | -0.9989 | 0.3592 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9045.075 | 1.2530 | 1.6301 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00806 | uM | 9045.075 | 0.8736 | 0.6974 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9045.075 | 1.1836 | 1.4543 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9045.075 | 1.0144 | 1.0351 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9045.075 | 1.1366 | 1.3365 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.04 | uM | 9045.075 | 0.9379 | 0.8501 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9045.075 | 1.1537 | 1.3791 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9045.075 | 0.9838 | 0.9606 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9045.075 | 0.2027 | -0.7120 | 0.8235 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9933.021 | 1.1656 | 2.1773 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9933.021 | 0.9132 | 0.5202 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9933.021 | 1.1152 | 1.7802 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9933.021 | 0.9867 | 0.9204 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9933.021 | 1.0707 | 1.4581 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9933.021 | 0.9121 | 0.5149 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9933.021 | 1.0970 | 1.6454 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9933.021 | 0.9966 | 0.9798 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9933.021 | 0.4463 | -0.8252 | 0.3311 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9953.011 | 0.9891 | 0.9539 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9953.011 | 0.9585 | 0.8275 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9953.011 | 1.0940 | 1.4214 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9953.011 | 1.1264 | 1.5768 | 0.4697 |