Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12192.155 | 0.8596 | 0.6324 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12192.155 | 0.8596 | 0.6324 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12192.155 | 0.9002 | 0.7369 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12192.155 | 0.9002 | 0.7369 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12192.155 | 0.9173 | 0.7812 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12192.155 | 0.9173 | 0.7812 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12192.155 | 0.9081 | 0.7574 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12192.155 | 0.9081 | 0.7574 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12192.155 | 0.9923 | 0.9793 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12192.155 | 0.9923 | 0.9793 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12192.155 | 0.8921 | 0.7159 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12192.155 | 0.8921 | 0.7159 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12192.155 | 0.9640 | 0.9039 | 0.7451 | |
| HCC2185 | TNBC | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12192.155 | 0.9640 | 0.9039 | 0.7451 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0000853 | uM | 10937.155 | 0.9180 | 0.8740 | 1.3142 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0000853 | uM | 10937.155 | 0.9180 | 0.8740 | 1.3142 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.000427 | uM | 10937.155 | 0.9636 | 0.9444 | 1.3142 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.000427 | uM | 10937.155 | 0.9636 | 0.9444 | 1.3142 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.00213 | uM | 10937.155 | 0.9173 | 0.8729 | 1.3142 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.00213 | uM | 10937.155 | 0.9173 | 0.8729 | 1.3142 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0107 | uM | 10937.155 | 0.9329 | 0.8970 | 1.3142 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0107 | uM | 10937.155 | 0.9329 | 0.8970 | 1.3142 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0533 | uM | 10937.155 | 0.9317 | 0.8951 | 1.3142 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0533 | uM | 10937.155 | 0.9317 | 0.8951 | 1.3142 | |
| HCC3153 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.267 | uM | 10937.155 | 0.9121 | 0.8648 | 1.3142 |