Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9953.011 | 0.9887 | 0.9521 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9953.011 | 1.0212 | 1.0912 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9953.011 | 1.0249 | 1.1074 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9953.011 | 0.9578 | 0.8247 | 0.4697 | |
| UACC-893 | HER2amp | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9953.011 | 0.3708 | -0.7581 | 0.4697 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7931.011 | 1.0615 | 1.0939 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7931.011 | 0.9776 | 0.9654 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7931.011 | 0.9779 | 0.9658 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7931.011 | 0.9024 | 0.8479 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7931.011 | 0.7601 | 0.6193 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7931.011 | 0.5998 | 0.3495 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7931.011 | 0.3988 | -0.0143 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7931.011 | 0.0912 | -0.6833 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7931.011 | 0.0147 | -0.9222 | 1.2993 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7932.011 | 1.0583 | 1.1295 | 0.9025 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7932.011 | 0.9332 | 0.8525 | 0.9025 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7932.011 | 1.0581 | 1.1291 | 0.9025 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7932.011 | 1.0019 | 1.0042 | 0.9025 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7932.011 | 0.8372 | 0.6425 | 0.9025 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7932.011 | 0.6201 | 0.1777 | 0.9025 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7932.011 | 0.4254 | -0.2242 | 0.9025 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7932.011 | 0.0722 | -0.8912 | 0.9025 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7932.011 | 0.0195 | -0.9746 | 0.9025 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9958.021 | 1.0369 | 1.1465 | 0.5129 | |
| ZR-75-1 | HR+ | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9958.021 | 0.9842 | 0.9389 | 0.5129 |