Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00806 | uM | 7902.075 | 0.8092 | 0.7951 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7902.075 | 1.2190 | 1.2128 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7902.075 | 0.9317 | 0.9291 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7902.075 | 1.0101 | 1.0103 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.04 | uM | 7902.075 | 0.7985 | 0.7830 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7902.075 | 0.7575 | 0.7356 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7902.075 | 0.5660 | 0.4956 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7902.075 | 0.2126 | -0.0929 | 1.9585 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 10266.011 | 1.2224 | 1.6762 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 10266.011 | 0.9484 | 0.8522 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 10266.011 | 1.1472 | 1.4407 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 10266.011 | 1.0093 | 1.0269 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 10266.011 | 1.1278 | 1.3811 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 10266.011 | 0.9595 | 0.8835 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 10266.011 | 0.8092 | 0.4712 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 10266.011 | 0.6264 | 0.0150 | 0.6895 | |
| MDA-MB-436 | TNBC | Basal B | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 10266.011 | 0.2195 | -0.7782 | 0.6895 | |
| MDA-MB-453 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7903.011 | 0.9667 | 0.9421 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7903.011 | 0.9657 | 0.9405 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7903.011 | 0.9578 | 0.9267 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7903.011 | 1.0163 | 1.0282 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7903.011 | 0.8147 | 0.6745 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7903.011 | 0.6757 | 0.4237 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7903.011 | 0.4683 | 0.0360 | 1.1535 | |
| MDA-MB-453 | TNBC | Luminal | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7903.011 | 0.0602 | -0.8249 | 1.1535 |