Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 66.7 | uM | 10755.146 | 0.8859 | 0.7200 | 0.8035 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12070.155 | 0.9527 | 0.9191 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0000853 | uM | 12070.155 | 0.9527 | 0.9191 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12070.155 | 0.9452 | 0.9061 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.000427 | uM | 12070.155 | 0.9452 | 0.9061 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12070.155 | 0.9956 | 0.9925 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.00213 | uM | 12070.155 | 0.9956 | 0.9925 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12070.155 | 0.9812 | 0.9680 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0107 | uM | 12070.155 | 0.9812 | 0.9680 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12070.155 | 0.9902 | 0.9832 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.0533 | uM | 12070.155 | 0.9902 | 0.9832 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12070.155 | 0.9587 | 0.9294 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 0.267 | uM | 12070.155 | 0.9587 | 0.9294 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12070.155 | 0.9707 | 0.9499 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 1.33 | uM | 12070.155 | 0.9707 | 0.9499 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12070.155 | 0.9156 | 0.8551 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 6.67 | uM | 12070.155 | 0.9156 | 0.8551 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12070.155 | 0.9802 | 0.9661 | 1.1729 | |
| CAMA-1 | HR+ | Luminal | PD184352 | MEK | MAPK | 33.3 | uM | 12070.155 | 0.9802 | 0.9661 | 1.1729 | |
| HCC1143 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0000853 | uM | 12112.155 | 1.0022 | 1.0025 | 1.7965 | |
| HCC1143 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.0000853 | uM | 12112.155 | 1.0022 | 1.0025 | 1.7965 | |
| HCC1143 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.000427 | uM | 12112.155 | 0.9769 | 0.9742 | 1.7965 | |
| HCC1143 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.000427 | uM | 12112.155 | 0.9769 | 0.9742 | 1.7965 | |
| HCC1143 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.00213 | uM | 12112.155 | 0.9366 | 0.9284 | 1.7965 | |
| HCC1143 | TNBC | Basal A | PD184352 | MEK | MAPK | 0.00213 | uM | 12112.155 | 0.9366 | 0.9284 | 1.7965 |