Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7857.011 | 0.0116 | -0.9716 | 1.0477 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7857.011 | 0.0072 | -0.9821 | 1.0477 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7860.011 | 1.0437 | 1.1236 | 0.7135 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7860.011 | 0.9941 | 0.9835 | 0.7135 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7860.011 | 1.0437 | 1.1236 | 0.7135 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7860.011 | 0.9908 | 0.9744 | 0.7135 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7860.011 | 0.9566 | 0.8794 | 0.7135 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 7860.011 | 0.9008 | 0.7276 | 0.7135 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 7860.011 | 0.1291 | -0.8866 | 0.7135 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 7860.011 | 0.0113 | -0.9963 | 0.7135 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 7860.011 | 0.0095 | -0.9971 | 0.7135 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 9501.011 | 0.9738 | 0.9437 | 0.9301 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 9501.011 | 1.0318 | 1.0684 | 0.9301 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 9501.011 | 1.0664 | 1.1431 | 0.9301 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 9501.011 | 0.9221 | 0.8330 | 0.9301 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 9501.011 | 0.8424 | 0.6632 | 0.9301 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 5.03 | uM | 9501.011 | 0.7470 | 0.4616 | 0.9301 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 25.2 | uM | 9501.011 | 0.0449 | -0.9290 | 0.9301 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 126 | uM | 9501.011 | 0.0092 | -0.9870 | 0.9301 | |
| HCC70 | TNBC | Basal A | Oxaliplatin | DNA cross-linker | DNA cross-linker | 629 | uM | 9501.011 | 0.0045 | -0.9939 | 0.9301 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00161 | uM | 7911.011 | 1.0531 | 1.0652 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.00805 | uM | 7911.011 | 1.0584 | 1.0715 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.0403 | uM | 7911.011 | 1.0578 | 1.0708 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 0.201 | uM | 7911.011 | 1.0707 | 1.0864 | 1.6150 | |
| HMT-3522 S1 | Unknown | Unknown | Oxaliplatin | DNA cross-linker | DNA cross-linker | 1.01 | uM | 7911.011 | 1.0273 | 1.0337 | 1.6150 |