Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T47D | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 7542.1 | 0.9754 | 0.9626 | 1.3201 | |
| T47D | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 7542.1 | 1.0059 | 1.0089 | 1.3201 | |
| T47D | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 7542.1 | 0.7084 | 0.5402 | 1.3201 | |
| T47D | HR+ | Luminal | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 7542.1 | 0.0086 | -0.9457 | 1.3201 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7544.093 | 0.9988 | 0.9981 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7544.093 | 0.8988 | 0.8349 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7544.093 | 0.9682 | 0.9485 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.0107 | uM | 7544.093 | 0.9379 | 0.8991 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.0533 | uM | 7544.093 | 0.9869 | 0.9789 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.267 | uM | 7544.093 | 0.9880 | 0.9806 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 1.33 | uM | 7544.093 | 0.8885 | 0.8179 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 6.67 | uM | 7544.093 | 0.8118 | 0.6900 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 33.3 | uM | 7544.093 | 0.0169 | -0.9258 | 1.2382 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.000171 | uM | 7545.1 | 0.9481 | 0.9087 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.000853 | uM | 7545.1 | 0.9527 | 0.9167 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.00427 | uM | 7545.1 | 0.9871 | 0.9774 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.0213 | uM | 7545.1 | 0.9426 | 0.8989 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.107 | uM | 7545.1 | 0.9268 | 0.8709 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 0.533 | uM | 7545.1 | 0.9369 | 0.8888 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 2.67 | uM | 7545.1 | 0.8621 | 0.7558 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 13.3 | uM | 7545.1 | 0.8240 | 0.6875 | 1.1396 | |
| T47DKBLUC | Unknown | Unknown | PD173074 | FGFR1/3 | RTK | 66.7 | uM | 7545.1 | 0.1387 | -0.6468 | 1.1396 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.0000853 | uM | 7547.093 | 0.9858 | 0.9744 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.000427 | uM | 7547.093 | 0.8258 | 0.6828 | 1.1087 | |
| UACC-812 | HER2amp | Luminal | PD173074 | FGFR1/3 | RTK | 0.00213 | uM | 7547.093 | 0.9080 | 0.8332 | 1.1087 |