Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 600MPE | HR+ | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 5899.065 | 0.9541 | 0.9160 | 1.0946 | |
| 600MPE | HR+ | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 5899.065 | 0.9130 | 0.8404 | 1.0946 | |
| 600MPE | HR+ | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 5899.065 | 0.9542 | 0.9161 | 1.0946 | |
| 600MPE | HR+ | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 5899.065 | 0.9187 | 0.8508 | 1.0946 | |
| 600MPE | HR+ | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 5899.065 | 0.9177 | 0.8491 | 1.0946 | |
| 600MPE | HR+ | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 5899.065 | 0.9552 | 0.9179 | 1.0946 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 5900.065 | 1.0749 | 1.0667 | 2.2026 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 5900.065 | 0.9948 | 0.9953 | 2.2026 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 5900.065 | 0.9717 | 0.9741 | 2.2026 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 5900.065 | 1.0658 | 1.0587 | 2.2026 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 5900.065 | 1.0498 | 1.0446 | 2.2026 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 5900.065 | 0.9583 | 0.9617 | 2.2026 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 5900.065 | 1.0152 | 1.0138 | 2.2026 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 5900.065 | 1.0106 | 1.0096 | 2.2026 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 5900.065 | 0.9267 | 0.9321 | 2.2026 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.00485 | uM | 5901.065 | 1.0041 | 1.0040 | 2.0114 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.0243 | uM | 5901.065 | 0.9946 | 0.9946 | 2.0114 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.121 | uM | 5901.065 | 0.9802 | 0.9802 | 2.0114 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 0.606 | uM | 5901.065 | 1.0697 | 1.0681 | 2.0114 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 3.03 | uM | 5901.065 | 0.9621 | 0.9619 | 2.0114 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 15.2 | uM | 5901.065 | 0.9714 | 0.9713 | 2.0114 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 75.8 | uM | 5901.065 | 1.0162 | 1.0160 | 2.0114 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 379 | uM | 5901.065 | 0.9807 | 0.9807 | 2.0114 | |
| AU565 | HER2amp | Luminal | PS-1145 | IKK | NFKB | 1890 | uM | 5901.065 | 1.0433 | 1.0426 | 2.0114 | |
| BT-20 | TNBC | Basal A | PS-1145 | IKK | NFKB | 0.00485 | uM | 5902.065 | 0.9301 | 0.8890 | 1.2690 |